| STT3A: Finding the sugar in Wnt signaling | |
| 論文作者 | He, DS; Hu, GH |
| 期刊/會議名稱 | CELL CHEMICAL BIOLOGY |
| 論文年度 | 2025 |
| 論文類別 | |
| 摘要 | Aberrant Wnt signaling activation occurs in various cancers but has limited druggable targets. In this issue of Cell Chemical Biology, He et al.(1) established a double death trap Wnt reporter system. Combined with genome-wide CRISPR screening, this approach identified STT3A as an essential Wnt signaling regulator with therapeutic potential. |
| 卷 | 32 |
| 影響因子 | 7.2 |
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